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Optical Rotation Testing

Optical Rotation Testing

At NJ Labs, we offer precise and reliable optical rotation testing services using our state-of-the-art Rudolph AutoPol V Automatic Polarimeter (APV-6W). This advanced analytical instrument is essential for identifying and verifying optically active compounds—making it a critical component of pharmaceutical testing, nutraceutical testing, and raw material quality control.

Whether you’re analyzing APIs, dietary supplement ingredients, or botanical extracts, our optical rotation services help ensure your products meet regulatory standards and label claims.

Optical Rotation Testing

What Is Optical Rotation Testing?

Optical rotation is the measurement of how a compound rotates plane-polarized light. This technique is widely used to:

  • Confirm the identity of compounds
  • Assess purity
  • Ensure consistency in manufacturing
  • Support regulatory compliance in cGMP pharmaceutical laboratories

Our team performs optical rotation analysis following USP, EP, and JP pharmacopeial methods to ensure data accuracy and regulatory acceptance.

Our Instrument: Rudolph AutoPol V Polarimeter (APV-6W)

NJ Labs uses the Rudolph AutoPol V, a premium polarimeter designed for high-accuracy testing in regulated environments. Key features include:

  • Automatic temperature control for consistent readings
  • Multi-wavelength capability to meet global testing standards
  • Full cGMP and 21 CFR Part 11 compliance
  • Secure digital audit trails and electronic data integrity
  • Touchscreen interface and customized methods for routine and custom testing

This polarimeter is regularly calibrated using traceable standards, providing highly accurate and reproducible results.

Industries We Serve

Our optical rotation testing supports clients across industries:

  • Pharmaceutical manufacturers
  • Nutraceutical and dietary supplement companies
  • Botanical and herbal product formulators
  • API and excipient suppliers

We offer both standalone optical rotation testing and integration within larger testing programs, including stability studies, batch release, and method validation.

We routinely test samples such as amino acids, vitamins, excipients, and herbal compounds where optical activity determines both identity and purity.

Why Choose NJ Labs for Optical Rotation Testing?

  • Over 85 years of analytical testing experience
  • FDA- and DEA-registered, and cGMP-compliant laboratory
  • Fast turnaround times and custom testing protocols
  • Full documentation support including Certificates of Analysis (COAs) and audit-ready records
  • Seamless integration with method development, validation, and regulatory submission

Request a Quote or Learn More

If you need optical rotation analysis as part of your raw material qualification, product development, or regulatory submission, NJ Labs is here to help. Contact us today to discuss your project or request a quote.

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