ICP-MS is an acronym for Inductive Coupled Plasma Mass Spectroscopy. ICP-MS is an analytical instrument that combines inductive coupled plasma technology with mass spectroscopy for elemental analysis by generation of ions.
It combines a high temperature Inductively Coupled Plasma (ICP-MS) source with a mass spectrometer (MS). The ICP source converts the atoms of the elements in the sample to ions that are separated and detected by mass spectrometer. The ICP-MS combines multi-element capabilities with detection limits equivalent or below that of GFAA and can obtain isotopic information. The instrument can detect metals at parts per billion (ppb) and parts per trillion (ppt) levels.
ICP-MS is a high-tech addition to elemental analysis that can replace more conventional instrumentation, such as atomic absorption, which has been around for many years, and is not very sensitive. However, given the sensitivity and reliability of ICP-MS testing, the FDA has been recommending it more frequently. Companies requiring ICP-MS testing must often create an ICP-MS protocol for a method and submit the protocol along with the product to a laboratory. However, at New Jersey Laboratories, we specialize in developing and validating custom methods for your products according to your specifications and then creating and writing ICP-MS protocols for you. We write comprehensive protocols which have satisfied regulatory requirements, and we work closely with our clients during the entirety of the project, which includes explaining our process every step of the way. Our reporting process is detailed, complete and designed to withstand FDA scrutiny.
At NJ Labs, we invest in advanced instrumentation to ensure the highest level of accuracy, sensitivity, and compliance in elemental analysis. Our state-of-the-art ICP-MS systems are at the core of our elemental impurity and trace metal detection capabilities.
We proudly operate:
These instruments allow us to break down complex sample matrices—such as your raw material or finished products including, botanicals, dietary supplements, pharmaceuticals, water, personal care products and other soluble samples —into a uniform solution ideal for trace metals analysis, to detect parts-per-trillion (ppt) levels across a wide range of sample types, with full compliance to regulatory standards.
At NJ Labs, we use the CEM MARS 6 Microwave Digestion System as a critical part of our Inductively Coupled Plasma Mass Spectrometry (ICP-MS) workflow. Accurate elemental analysis begins with precise, complete sample preparation—and the MARS 6 delivers just that.
The Agilent 7800 ICP-MS offers unmatched reliability and robust performance for routine trace element analysis. Key features include:
This system is ideal for high-throughput labs requiring consistent, accurate results in pharmaceutical, food, and environmental applications.
The Agilent 8900 ICP-MS is a next-generation triple quadrupole ICP-MS (ICP-QQQ), providing advanced performance for ultra-trace analysis and method development. Features include:
With the Agilent 8900, NJ Labs can perform cutting-edge elemental analysis with confidence, even in samples where traditional single quadrupole ICP-MS may fall short.
Advanced instrumentation isn’t just about performance—it’s about data integrity, reproducibility, and compliance. At NJ Labs, every result generated by our ICP-MS systems is backed by a rigorous calibration, qualification, and maintenance program, ensuring reliability and full alignment with CGMP, USP <232>/<233>, and ICH Q2standards.
