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High-Performance Liquid Chromatography (HPLC) Testing

High-Performance Liquid Chromatography (HPLC) Testing

Precision You Can Trust. Compliance You Can Count On.

At NJ Labs, High-Performance Liquid Chromatography (HPLC) is at the core of our analytical testing capabilities. From raw materials to finished products, our HPLC systems deliver accurate, reproducible data that meets the highest regulatory standards—helping our clients stay compliant and confident in their products.

Our lab is equipped with an extensive fleet of HPLC systems that are validated, calibrated, and maintained under strict FDA protocols. This enables us to efficiently handle a wide variety of sample types and testing needs—from routine analysis to complex custom methods.

High-Performance Liquid Chromatography (HPLC) Testing

Our HPLC Instrumentation

We utilize a diverse suite of state-of-the-art HPLC instruments to provide flexible, high throughput testing across multiple industries:

  • HP Agilent 1100 HPLC Systems
    A trusted workhorse for routine testing and compendial methods.
  • Agilent 1260 Infinity HPLC Systems
    Designed for high precision, speed, and sensitivity in demanding applications.
  • Agilent A1260 HPLC Systems
    An advanced platform for complex separations and customizable method development.
  • Waters Alliance HPLC Systems
    Industry-standard systems for pharmaceutical and nutraceutical analyses.

Each instrument is managed under a comprehensive qualification and preventive maintenance program to ensure peak performance and reliable results at every stage.

Detector Capabilities

We pair our HPLC systems with a range of detectors, expanding our ability to tailor each analysis to your specific analyte, matrix, and regulatory requirements:

  • Refractive Index Detectors (RID)
  • Fluorescence Detector (FLD)
  • Thermal Conductivity Detectors (TCD)
  • Flame Ionization Detectors (FID)

What We Test With HPLC

  • API quantification & impurity profiling
  • Raw material identification
  • Botanical testing
  • Finished product assay & label claim verification
  • Stability studies and method validation

Our team develops and executes methods following USP, AOAC, FCC, EP, JP, and other custom testing methods, ensuring compliance and regulatory readiness.

Why Choose NJ Labs?

When you work with NJ Labs, you’re not just accessing powerful instrumentation—you’re gaining a partner with decades of regulatory expertise, scientific integrity, and a commitment to data transparency. We don’t just generate results. We help guide your products to market with confidence.

Let’s talk about how our HPLC capabilities can help you meet your testing goals.

Frequently Asked Questions

What is HPLC?

High-Performance Liquid Chromatography (HPLC) is a versatile analytical technique that helps separate, identify, and quantify compounds in diverse samples across industries. Unlike Gas Chromatography (GC), which uses gases as the mobile phase, HPLC utilizes liquids, such as phosphate buffers, to carry the standard and sample solutions through the system. This liquid-based approach allows HPLC to focus on ensuring products meet labeled specifications by assaying active ingredients. HPLC is also essential for monitoring product potency over time, as it can detect the breakdown of compounds due to aging or storage conditions, which is crucial for maintaining quality and efficacy.

How does HPLC work?
What is the difference between HPLC and UPLC?
What are the components of HPLC method validation & verification?

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